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Filtered Search Results
Selleck Chemical LLC K-Ras
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K-Ras(G12C) inhibitor 6 is an allosteric and selective inhibitor of oncogenic K-Ras(G12C)
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Medchemexpress LLC TFMB-(R)-2-HG | 1445700-01-5 | 98.3% | 50 MG
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TFMB-(R)-2-HG is a cell membrane-permeable (R)-2-HG and an acute myeloid leukemia (AML) oncogenic factor. It functions by competitively inhibiting alpha-ketoglutarate-dependent dioxygenases, such as KDM2B and FTO. This compound impairs cell differentiation when estrogen is withdrawn and is utilized in research concerning acute myeloid leukemia and glioma.
- Cell membrane-permeable (R)-2-HG
- Acute myeloid leukemia (AML) oncogenic factor
- Competitively inhibits alpha-ketoglutarate-dependent dioxygenases (e.g., KDM2B, FTO)
- Impairs cell differentiation upon estrogen withdrawal
- Useful in acute myeloid leukemia research
- Useful in glioma research
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Medchemexpress LLC HY-10121 10mg Medchemexpress, Asenapine CAS:65576-45-6 Purity:>98%
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Medchemexpress, HY-10121 10mg Asenapine CAS:65576-45-6 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Lucitanib | 1058137-23-7 | C26H25N3O4 | 100 MG
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Lucitanib (E-3810) is a novel dual inhibitor of VEGFR and FGFR, potently and selectively inhibiting multiple receptors. It is suitable for use in various laboratory applications, including the manufacture of substances.
- Inhibits VEGFR1 with an IC50 of 7 nM
- Inhibits VEGFR2 with an IC50 of 25 nM
- Inhibits VEGFR3 with an IC50 of 10 nM
- Inhibits FGFR1 with an IC50 of 17.5 nM
- Inhibits FGFR2 with an IC50 of 82.5 nM
- Targeted for cancer research
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Medchemexpress LLC 2,4-Pyrimidinediamine, N2-[4-[(3-aminopropyl)amino]phenyl]-N4-(5-cyclopropyl-1H-pyrazol-3-yl) HCl | 2700435-52-3 | 99.5% | 400.91 | 50 MG
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VEGFR-2-IN-5 hydrochloride is an off-white to light yellow solid. It is identified as a VEGFR2 inhibitor, extracted from patent WO2013055780A1. This compound targets VEGFR, demonstrating activity against VEGFR2.
- Acts as a VEGFR2 inhibitor.
- Appearance: off-white to light yellow solid.
- Complies with given specifications.
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eMolecules 1992047-64-9 | Medchem Express | MS023 (dihydrochloride) | 2mg | 459606982 | HY-19615B | MFCD30290157 | 360.32 | C17H27Cl2N3O
Ambeed | 56-Dimethylpyrimidin-4-ol | 100mg | 521395288 | A111573 | 34916-78-4 | MFCD00234217 | 124.143 | C6H8N2O
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Medchemexpress LLC 3-methoxy-N-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-morpholinoethoxy)phenyl)benzamide | 887936-68-7 | 98.9% | 436.50 g/mol | C24H28N4O4 | 100 MG
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Temanogrel is a research-grade small molecule that acts as a highly selective antagonist of the serotonin 5-HT2A receptor (reported Ki = 4.9 nM). Supplied as a solid powder for in vitro and preclinical research, it is provided at high purity for biochemical and pharmacological studies.
- Highly selective 5-HT2A receptor antagonist (Ki = 4.9 nM).
- Intended for research use only; not for human therapeutic use.
- High purity (98.94%) solid powder, white to light yellow.
- Molecular formula C24H28N4O4; molecular weight 436.50 g/mol.
- Storage: powder at -20°C (up to 3 years) or 4°C (up to 2 years); in solvent store at -80°C (6 months) or -20°C (1 month).
- Available in small milligram pack sizes suitable for laboratory studies.
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Medchemexpress LLC 1-(4-fluorophenyl)-N-((2-(methylsulfonyl)pyridin-4-yl)methyl)-1H-pyrazolo[3,4-c]pyridine | 1220026-26-5 | 99.7% | 425.44 | C20H16FN5O3S | 50MG
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CCR1 antagonist 9 is a potent, selective small-molecule antagonist of the chemokine receptor CCR1 intended for research use. It inhibits CCR1-mediated calcium flux with an IC50 of 6.8 nM, reduces CCR1-dependent chemotaxis in THP-1 cells, and shows measurable hERG activity.
- Potent CCR1 inhibition with IC50 of 6.8 nM in calcium flux assay.
- Inhibits CCR1 chemotaxis of THP-1 cells with IC50 of 28 nM.
- Displays hERG activity with IC50 of 30 μM.
- High purity (99.7%) and chemical formula C20H16FN5O3S.
- Molecular weight 425.44 g/mol.
- Available in multiple solid and solution pack sizes with COA and SDS documentation.
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Medchemexpress LLC Epertinib hydrochloride | 2071195-74-7 | 98.2% | 596.48 g/mol | C30H28Cl2FN5O3 | 100 MG
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Epertinib hydrochloride is the hydrochloride salt of epertinib, a potent, orally active, reversible, and selective inhibitor of EGFR, HER2, and HER4. It is provided for preclinical research to evaluate signaling pathways and antitumor efficacy and is compatible with click-chemistry applications because of an alkyne functional group.
- Potent, selective tyrosine kinase inhibitor of EGFR, HER2, and HER4.
- Used in preclinical antitumor and signaling research.
- Contains an alkyne moiety compatible with copper-catalyzed azide-alkyne cycloaddition (CuAAC).
- Supplied as a light yellow to yellow solid with high purity.
- Stable under recommended storage: 4°C sealed; in solvent -80°C (6 months), -20°C (1 month).
- Molecular weight 596.48 g/mol; molecular formula C30H28Cl2FN5O3.
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eMolecules 1644543-95-2 | Medchem Express | S65487 (hydrochloride) | 5mg | 694125052 | HY-138697B | 753.73 | C41H42Cl2N6O4
Ambeed | 1-Boc-4-(Hydroxymethyl)-4-methylpiperidine | 1g | 525022997 | A123210 | 236406-21-6 | MFCD08062516 | 229.320 | C12H23NO3
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Selleck Chemical LLC Ansamitocin p-3 (Maytansinol isobutyrate. NSC292222) S2447-5mg
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Ansamitocin p-3 (Maytansinol isobutyrate NSC292222 Antibiotic C 15003P3) is a potent inhibitor of tubulin polymerization with IC50 of 3 4 M
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Biotium DIOC23 100MG
DIOC23 100MG
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eMolecules 129558-76-5 | Medchem Express | Tolfenpyrad | 100mg | 446268570 | HY-17516 | MFCD08273850 | 383.88 | C21H22ClN3O2
Medchem Express | Ro 46-2005 | 5mg | 446269889 | HY-19529 | 150725-87-4 | MFCD00918670 | 473.540 | C23H27N3O6S
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Medchemexpress LLC Arn 077 (Urb913) | 1373625-34-3 | 98.8% | 100MG
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Arn 077 (Urb913) | 1373625-34-3 | 98.8% | 100MG
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Medchemexpress LLC LYP-IN-1 | 1404436-51-6 | MFCD34567163 | 99.8% | 501.91 g/mol | C28H20ClNO6 | 5 MG
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LYP-IN-1 is a potent, selective inhibitor of lymphoid tyrosine phosphatase used in biochemical and cellular studies to probe T-cell and mast cell signaling. The compound contains an alkyne moiety enabling copper-catalyzed azide-alkyne cycloaddition for probe development and labeling in chemical biology applications.
- Potent and selective LYP inhibition (Ki 110 nM; IC50 0.259 μM).
- Alkyne handle for copper-catalyzed click chemistry applications.
- High purity suitable for biochemical and cellular assays.
- Soluble in DMSO up to 2 mg/mL with mild heating and sonication.
- Stable when stored as powder at -20°C for extended periods.
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